Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 4/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 4/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MSN | P26038 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | GAPDH | P04406 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416662 | 1.00 | CDC25B (0.42) | CDC25BCYP2C9NR4A1PTPN7HSPA1A | |
| SCHEMBL10545096 | 0.74 | CDC25B (0.50) | CDC25BCYP2C9NR4A1PTPN7HSPA1A | |
| SCHEMBL7418984 | 0.71 | CYP2C9 (0.39) | CDC25BCYP2C9BRD4KDM4EMAPT | |
| SCHEMBL9509212 | 0.71 | CYP2C9 (0.39) | CDC25BCYP2C9BRD4KDM4EMAPT | |
| SCHEMBL5196202 | 0.67 | ALDH1A1 (0.50) | CDC25BCYP2C9NR4A1KDM4EPOLB | |
| SCHEMBL8487411 | 0.66 | TSHR (0.45) | CDC25BCYP2C9TDP1KDM4EMEN1 | |
| SCHEMBL8133538 | 0.66 | CYP2C9 (0.42) | CDC25BCYP2C9NR4A1BRD4MAPT | |
| SCHEMBL2926588 | 0.65 | BRD4 (0.51) | CYP2C9NR4A1BRD4KDM4EMAPT | |
| SCHEMBL10590358 | 0.65 | CYP2C9 (0.41) | CDC25BCYP2C9BRD4MEN1MAPT | |
| SCHEMBL10591479 | 0.65 | CYP2C9 (0.41) | CDC25BCYP2C9BRD4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288731-A | Antiemetics, antiserotonine agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-02-22 | — | — | US | disclosed |
| WO-1992009284-A1 | 2,6-METHANO-2H-1-BENZOXOCINCARBOXAMIDES AS 5-HT3-ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-06-11 | — | — | WO | disclosed |