Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13771349 | 0.89 | TP53 (0.40) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL13771143 | 0.88 | TP53 (0.42) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL13771295 | 0.88 | TP53 (0.42) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL1491596 | 0.88 | TP53 (0.42) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL28554049 | 0.86 | CCNA2 (0.36) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL31051156 | 0.86 | ALDH1A1 (0.44) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL20764812 | 0.86 | ALDH1A1 (0.39) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL16569372 | 0.86 | ALDH1A1 (0.39) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL30940157 | 0.85 | CCNA2 (0.38) | CCNA2CDK2CCNA1CDK5CDK5R1 | |
| SCHEMBL31051142 | 0.84 | SMN1; SMN2 (0.39) | CCNA2CDK2CCNA1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171422-A1 | MMP INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000063165-A1 | MMP INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-26 | — | — | WO | disclosed |