SCHEMBL7416829

SCHEMBL7416829

O=C(O)C1(c2ccc(CCl)s2)CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7422650 0.72 HDAC4 (0.34) HDAC4
SCHEMBL11626640 0.64 HPGD (0.50)
SCHEMBL1402106 0.64 DAO (0.54)
SCHEMBL25381715 0.63 DAO (0.44)
SCHEMBL1258558 0.62
SCHEMBL16113395 0.61 HDAC4 (0.68) HDAC4
SCHEMBL11624199 0.60 HPGD (0.35)
SCHEMBL31169149 0.60 DAO (0.44)
SCHEMBL17065257 0.59 GSK3B (0.60)
SCHEMBL4590565 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995002596-A1 AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS PFIZER INC. (US) 1995-01-26 WO claimed