Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240032 | 0.78 | OPRM1 (0.39) | — | |
| SCHEMBL7416829 | 0.72 | HDAC4 (0.33) | HDAC4 | |
| SCHEMBL7422656 | 0.71 | DPP4 (0.34) | DPP4ALDH1A1KDM4E | |
| SCHEMBL15898220 | 0.69 | ALDH1A1 (0.38) | DPP4ALDH1A1KDM4E | |
| SCHEMBL7423695 | 0.66 | OPRM1 (0.42) | — | |
| SCHEMBL15898586 | 0.66 | ALDH1A1 (0.40) | DPP4ALDH1A1KDM4E | |
| SCHEMBL15898234 | 0.65 | ALDH1A1 (0.32) | ALDH1A1KDM4E | |
| SCHEMBL7419666 | 0.64 | OPRM1 (0.46) | — | |
| 2,5-Thiophenenedicarboxaldehyde SCHEMBL178830 | 0.63 | — | — | |
| SCHEMBL855403 | 0.63 | KDM4E (0.38) | DPP4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | claimed |