SCHEMBL7416945

SCHEMBL7416945

CCCOC(COCC[O])OC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3757668 0.86
SCHEMBL7415858 0.84 HSD17B10 (0.34) HSD17B10TDP1
SCHEMBL28797362 0.83 HSD17B10 (0.32) HSD17B10TDP1
SCHEMBL10433116 0.83
SCHEMBL11251941 0.77 USP2 (0.34) HSD17B10TDP1
SCHEMBL7418215 0.77 LPAR1 (0.45)
SCHEMBL27432252 0.76
Methacrylic Acid SCHEMBL27626643 0.75 HSD17B10 (0.36) HSD17B10TDP1
SCHEMBL4538926 0.75 HSD17B10 (0.50) HSD17B10TDP1
SCHEMBL7419737 0.74 LPAR1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5594006-A SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
WO-1994021612-A1 CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-09-29 WO disclosed