Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097325 | 0.92 | THRB (0.33) | HSD17B10 | |
| SCHEMBL703310 | 0.87 | LPAR1 (0.41) | — | |
| SCHEMBL7416945 | 0.84 | HSD17B10 (0.34) | HSD17B10TDP1 | |
| SCHEMBL29195105 | 0.83 | HSD17B10 (0.34) | HSD17B10TDP1 | |
| SCHEMBL9624071 | 0.83 | HSD17B10 (0.48) | HSD17B10TDP1 | |
| SCHEMBL3757668 | 0.82 | — | — | |
| SCHEMBL4538926 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1 | |
| SCHEMBL11792372 | 0.80 | ALDH1A1 (0.44) | HSD17B10TDP1 | |
| SCHEMBL7419737 | 0.78 | LPAR1 (0.46) | — | |
| SCHEMBL15283632 | 0.78 | CYP3A4 (0.47) | HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |