Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840247 | 0.88 | HRH3 (0.42) | PARP1KCNH2GPR84MAPK1 | |
| Hydrochloric Acid SCHEMBL28183399 | 0.86 | HRH3 (0.41) | PARP1KCNH2GPR84MAPK1GSK3B | |
| Acetic Acid SCHEMBL27806863 | 0.83 | PARP1 (0.39) | PARP1KCNH2GPR84 | |
| SCHEMBL28272718 | 0.83 | KCNH2 (0.48) | KCNH2GPR84 | |
| SCHEMBL27934300 | 0.83 | KCNH2 (0.48) | KCNH2GPR84 | |
| SCHEMBL3841613 | 0.83 | HRH3 (0.41) | PARP1KCNH2GPR84MAPK1GSK3B | |
| SCHEMBL3841860 | 0.83 | HRH3 (0.41) | PARP1KCNH2PDPK1MAPK1 | |
| SCHEMBL1063754 | 0.83 | KCNH2 (0.47) | KCNH2GPR84 | |
| SCHEMBL7657253 | 0.83 | TLR8 (0.40) | PARP1KCNH2HSD11B1ADORA3ADORA2A | |
| SCHEMBL9214238 | 0.83 | TLR8 (0.43) | PARP1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674879-A | Compositions including and methods of using conformationally restricted angiotensin II antagonist | G.D. SEARLE & CO. (US) | 1997-10-07 | — | — | US | disclosed |
| US-5426105-A | Cardiovascular disorders | G.D. SEARLE & CO. (US) | 1995-06-20 | — | — | US | disclosed |