Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12532887 | 0.91 | MAPK1 (0.36) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL31460072 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| Hydrochloric Acid SCHEMBL31459957 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL12532886 | 0.82 | MAPKAPK2 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL31409379 | 0.81 | TP53 (0.42) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL24928462 | 0.81 | TSHR (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL23115927 | 0.80 | AURKA (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL30860986 | 0.79 | PDE4A (0.39) | KDM4EALDH1A1HPGDHSD17B10SMPD1 | |
| SCHEMBL171958 | 0.78 | SMPD1 (0.41) | SMPD1CNR1CNR2 | |
| SCHEMBL20661071 | 0.75 | CYP11B1 (0.36) | KDM4EALDH1A1HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821241-A | INHIBIT BINDING OF FIBRINOGEN TO BLOOD PLATELETS, INHIBIT AGGREGATION OF BLOOD PLATELETS, PREVENT OR TREAT THROMBUS OR EMBOLUS FORMATION | MERCK & CO., INC. (US) | 1998-10-13 | — | — | US | disclosed |
| WO-1994018981-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |