Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.68 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281797 | 1.00 | HRH1 (0.68) | HRH1HTR2ARIPK1LMNAAOC3 | |
| Hydrochloric Acid SCHEMBL326015 | 0.98 | HRH1 (0.65) | HRH1HTR2ARIPK1LMNAAOC3 | |
| SCHEMBL7373079 | 0.93 | HRH1 (0.59) | HRH1HTR2ARIPK1LMNAAOC3 | |
| SCHEMBL3179795 | 0.88 | HRH1 (0.62) | HRH1HTR2ARIPK1LMNAAOC3 | |
| SCHEMBL42066 | 0.88 | HRH1 (0.62) | HRH1HTR2ARIPK1LMNAAOC3 | |
| SCHEMBL232834 | 0.88 | HRH1 (0.62) | HRH1HTR2ARIPK1LMNAAOC3 | |
| SCHEMBL27928248 | 0.86 | HRH1 (0.60) | HRH1HTR2ARIPK1LMNAAOC3 | |
| Hydrochloric Acid SCHEMBL4374172 | 0.86 | HRH1 (0.60) | HRH1HTR2ARIPK1LMNAAOC3 | |
| Hydrochloric Acid SCHEMBL16032107 | 0.86 | HRH1 (0.60) | HRH1HTR2ARIPK1LMNAAOC3 | |
| Bromide SCHEMBL28648396 | 0.86 | HRH1 (0.60) | HRH1HTR2ARIPK1LMNAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666842-A1 | HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-08-16 | — | — | EP | disclosed |
| WO-1993023368-A1 | UREA-CONTAINING HYDROXYETHYLAMINE COMPOUNDS AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1993-11-25 | — | — | WO | disclosed |