Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179795 | 0.98 | HRH1 (0.62) | HRH1RIPK1LMNAAOC3HTR2A | |
| SCHEMBL42066 | 0.98 | HRH1 (0.62) | HRH1RIPK1LMNAAOC3HTR2A | |
| SCHEMBL232834 | 0.98 | HRH1 (0.62) | HRH1RIPK1LMNAAOC3HTR2A | |
| Hydrochloric Acid SCHEMBL4374172 | 0.95 | HRH1 (0.60) | HRH1RIPK1LMNAAOC3HTR2A | |
| SCHEMBL27928248 | 0.95 | HRH1 (0.60) | HRH1RIPK1LMNAAOC3HTR2A | |
| Hydrochloric Acid SCHEMBL16032107 | 0.95 | HRH1 (0.60) | HRH1RIPK1LMNAAOC3HTR2A | |
| SCHEMBL4281797 | 0.86 | HRH1 (0.68) | HRH1RIPK1LMNAAOC3HTR2A | |
| SCHEMBL7417534 | 0.86 | HRH1 (0.68) | HRH1RIPK1LMNAAOC3HTR2A | |
| Cadaverine Tartrate SCHEMBL9851431 | 0.86 | HRH1 (0.50) | HRH1RIPK1LMNAAOC3HTR2A | |
| Hydrochloric Acid SCHEMBL326015 | 0.84 | HRH1 (0.65) | HRH1RIPK1LMNAAOC3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113543752-A | Multi-dose ophthalmic fluid delivery system | 科达莱昂治疗公司 | 2021-10-22 | — | — | CN | disclosed |