Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797863 | 0.86 | KMT2A (0.46) | KMT2ACYP1A2GAACYP2C9PKM | |
| SCHEMBL14935912 | 0.81 | GSR (0.50) | GSRBLMTRPA1LMNA | |
| SCHEMBL14935978 | 0.81 | GSR (0.50) | GSRBLMTRPA1LMNA | |
| SCHEMBL16398170 | 0.81 | GSR (0.50) | GSRBLMTRPA1LMNA | |
| SCHEMBL4426985 | 0.80 | GSR (0.57) | GSRBLMTRPA1CYP2D6SRC | |
| SCHEMBL8602813 | 0.79 | GSR (0.49) | GSRBLMTRPA1LMNA | |
| SCHEMBL6898472 | 0.77 | HCAR2 (0.49) | KMT2ACYP1A2GAACYP2C9PKM | |
| SCHEMBL187761 | 0.77 | KMT2A (0.47) | KMT2ACYP1A2GAACYP2C9PKM | |
| SCHEMBL13843585 | 0.76 | TRPA1 (0.47) | GSRKMT2ABLMTRPA1LMNA | |
| SCHEMBL14945485 | 0.76 | TRPA1 (0.47) | GSRKMT2ABLMTRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173415-A1 | DIPHENYLUREA DERIVATIVES | AstraZeneca AB (SE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064866-A1 | DIPHENYLUREA DERIVATIVES | ASTRAZENECA AB (SE) | 2000-11-02 | — | — | WO | disclosed |