Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396373 | 0.91 | TSHR (0.39) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL24083149 | 0.83 | HTT (0.45) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL15159038 | 0.83 | HTT (0.45) | CES2HTTMEN1THRBKMT2A | |
| SCHEMBL4393747 | 0.82 | — | — | |
| SCHEMBL4398071 | 0.82 | DNM1 (0.50) | LPAR1LPAR3DNM1LPAR2 | |
| SCHEMBL1402431 | 0.82 | DNM1 (0.50) | LPAR1LPAR3DNM1LPAR2 | |
| SCHEMBL8896345 | 0.82 | DNM1 (0.50) | LPAR1LPAR3DNM1LPAR2 | |
| SCHEMBL3503799 | 0.82 | DNM1 (0.50) | LPAR1LPAR3DNM1LPAR2 | |
| SCHEMBL8045961 | 0.82 | DNM1 (0.50) | LPAR1LPAR3DNM1LPAR2 | |
| SCHEMBL4401469 | 0.82 | DNM1 (0.50) | LPAR1LPAR3DNM1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |