Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354337 | 0.80 | GRIN2D (0.42) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8911220 | 0.80 | GRIN2D (0.42) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL7414612 | 0.79 | CA12 (0.47) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL7351758 | 0.78 | MEN1 (0.36) | HPGDPOLB | |
| SCHEMBL8911406 | 0.75 | GRIK1 (0.65) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7353512 | 0.74 | GRIA1 (0.50) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL1662279 | 0.74 | GRIA2 (1.00) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL30905563 | 0.74 | GRIA2 (1.00) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8911413 | 0.73 | PDE2A (0.43) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8912067 | 0.73 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |