SCHEMBL741780

SCHEMBL741780

CCCCCCCCCCS(=O)(=O)Cl

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.56
CA2 P00918 6/20 0.50
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
EPHX2 P34913 1/20 0.42
ALDH1A1 P00352 1/20 0.41
CES1 P23141 2/20 0.41
CES2 O00748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7252868 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL1114761 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL744300 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL11719482 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL11381720 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL94158 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL11411801 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL743460 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL9834817 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2
SCHEMBL31126199 1.00 FAAH (0.56) FAAHCA2TSHRTHRBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011045807-A2 A NOVEL PROCESS TO MANUFACTURE (2R,3S)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL NEULAND LABORATORIES LTD. (IN) 2011-04-21 WO claimed
WO-2010115869-A1 PROPOFOL PHOSPHONYL DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS SEPS PHARMA N.V. (BE) 2010-10-14 WO claimed
WO-2025075722-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-04-10 WO disclosed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
US-20240307863-A1 STYRENIC FLUOROPOLYMERS AND METHODS FOR MAKING AND USING SAME University of Louisiana Lafayette (US) 2024-09-19 US disclosed
US-11702394-B2 Inhibitors of phospholipid synthesis and methods of use THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-07-18 US disclosed
CN-106661084-B Macrocyclic broad spectrum antibiotics 阿奇克斯制药公司 2021-08-31 CN disclosed
EP-3145944-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2021-05-05 EP disclosed
US-10392422-B2 Macrocyclic broad spectrum antibiotics RQX PHARMACEUTICALS, INC. (US) 2019-08-27 US disclosed
US-10351595-B2 2019-07-16 US disclosed
CN-109337657-A The improved silica material and its preparation method and application of bits agent is taken with fluorine carbon activity agent class super-amphiphobic suitable for water-base drilling fluid 中国石油大学(北京) 2019-02-15 CN disclosed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 WO disclosed
WO-1992016495-A1 AMIDE ANTIOXIDANTS ETHYL CORPORATION (US) 1992-10-01 WO disclosed
US-5103054-A Polymer antioxidant ETHYL CORPORATION (US) 1992-04-07 US disclosed
US-5102934-A For use with ethylenically unsaturated hydrocarbons ETHYL CORPORATION (US) 1992-04-07 US disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
US-RE29577-E Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-4056622-A MICROBIOCIDES, FUNGICIDES, BACTERICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-11-01 US disclosed
US-3963763-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3932419-A QUINOLINE DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702394-B2 Inhibitors of phospholipid synthesis and methods of use LCAT, AGPAT2, GNPAT FAAH 586/4885CA2 2799/4885TSHR 2550/4885
US-10351595-B2 MRPL21, PRSS1, PEPD FAAH 2818/4885CA2 3717/4885TSHR 4401/4885
US-10392422-B2 Macrocyclic broad spectrum antibiotics MRPL21, PEPD, CTSC FAAH 3193/4885CA2 4501/4885TSHR 4174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.