SCHEMBL7418522

SCHEMBL7418522

CCOC(=O)CCCCN1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 5/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
MAPT P10636 2/20 0.47
ALOX15 P16050 1/20 0.47
HRH3 Q9Y5N1 3/20 0.47
KCNH2 Q12809 1/20 0.46
KDM4E B2RXH2 1/20 0.46
RAB9A P51151 1/20 0.45
POLB P06746 1/20 0.44
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24001256 0.98 ALDH1A1 (0.50) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL7418518 0.98 ALDH1A1 (0.50) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL24001095 0.98 ALDH1A1 (0.50) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL24757426 0.98 CYP1A2 (0.48) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL27065452 0.97 ALDH1A1 (0.48) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL24757440 0.95 CYP1A2 (0.48) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL856060 0.95 CYP1A2 (0.56) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL1863035 0.95 CYP1A2 (0.56) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
Bromide SCHEMBL741360 0.93 CYP1A2 (0.55) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL1855324 0.93 CYP1A2 (0.53) CYP1A2MAPK1SMN1; SMN2ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815103-A1 TRYPSIN AND THROMBIN INHIBITORS Novartis AG (CH) 1998-01-07 EP disclosed
WO-1996029327-A1 TRYPSIN AND THROMBIN INHIBITORS NOVARTIS AG (CH) 1996-09-26 WO disclosed