Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421632 | 0.80 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7418078 | 0.78 | PDE4D (1.00) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7422584 | 0.78 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7422190 | 0.77 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7423546 | 0.77 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7423419 | 0.75 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7413548 | 0.75 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7418696 | 0.73 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL7425456 | 0.73 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DDRD2 | |
| SCHEMBL13350317 | 0.73 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |