Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437277 | 0.77 | TACR1 (0.42) | CES2TACR1IDO1TDO2MAPT | |
| SCHEMBL14972564 | 0.75 | TACR1 (0.43) | TACR1TACR3 | |
| SCHEMBL13484088 | 0.75 | TACR1 (0.43) | TACR1TACR3 | |
| SCHEMBL4528004 | 0.75 | TACR1 (0.43) | TACR1TACR3 | |
| SCHEMBL18106081 | 0.75 | TACR1 (0.41) | CES2TACR1IDO1TDO2MAPT | |
| SCHEMBL17994000 | 0.75 | TACR1 (0.41) | CES2TACR1IDO1TDO2MAPT | |
| SCHEMBL13476400 | 0.75 | TACR1 (0.41) | CES2TACR1IDO1TDO2MAPT | |
| SCHEMBL20530516 | 0.74 | MAPT (0.41) | CES2TACR1ACP1PTPN7PTPN12 | |
| SCHEMBL20730205 | 0.73 | TACR1 (0.40) | CES2TACR1IDO1TDO2MAPT | |
| SCHEMBL16953807 | 0.73 | TACR1 (0.40) | CES2TACR1IDO1TDO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |