Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419152 | 1.00 | SLC1A1 (0.60) | SLC1A1TACR1ALDH1A1IDO1CA1 | |
| Hydrochloric Acid SCHEMBL11024444 | 0.98 | SLC1A1 (0.59) | SLC1A1TACR1ALDH1A1IDO1CA1 | |
| Hydrochloric Acid SCHEMBL29556904 | 0.98 | SLC1A1 (0.59) | SLC1A1TACR1ALDH1A1IDO1CA1 | |
| Hydrochloric Acid SCHEMBL20996762 | 0.98 | SLC1A1 (0.59) | SLC1A1TACR1ALDH1A1IDO1CA1 | |
| SCHEMBL7310424 | 0.89 | SLC1A1 (0.56) | SLC1A1TACR1ALDH1A1CA1KMT2A | |
| SCHEMBL13198428 | 0.89 | SLC1A1 (0.56) | SLC1A1TACR1ALDH1A1CA1KMT2A | |
| SCHEMBL16200527 | 0.88 | SLC1A1 (0.59) | SLC1A1TACR1ALDH1A1IDO1CA1 | |
| SCHEMBL23947614 | 0.88 | ALDH1A1 (0.52) | SLC1A1ALDH1A1IDO1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL7307012 | 0.87 | SLC1A1 (0.55) | SLC1A1TACR1ALDH1A1IDO1CA1 | |
| SCHEMBL2059074 | 0.87 | SLC1A1 (0.57) | SLC1A1TACR1ALDH1A1CA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912786-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912786-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-27 | — | — | US | disclosed |
| WO-2022191338-A1 | LEVODOPA-PRODRUGS AND CARBIDOPA-PRODRUGS FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2022-09-15 | — | — | WO | disclosed |
| US-20220119444-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | Sanford Burnham Prebys Medical Discovery Institute | 2022-04-21 | — | — | US | disclosed |
| US-11111270-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-09-07 | — | — | US | disclosed |
| US-10864217-B2 | Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-12-15 | — | — | US | disclosed |
| US-20200317731-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | Sanford Burnham Prebys Medical Discovery Institute | 2020-10-08 | — | — | US | disclosed |
| US-20200121693-A1 | Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2020-04-23 | — | — | US | disclosed |
| US-10544188-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-01-28 | — | — | US | disclosed |
| WO-2019152688-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| US-5475085-A | Unlimited array of peptides having reverse turn mimetics | MOLECUMETICS, LTD. (US) | 1995-12-12 | — | — | US | disclosed |
| EP-0656907-A1 | CONFORMATIONALLY RESTRICTED MIMETICS OF REVERSE TURNS AND PEPTIDES CONTAINING THE SAME | MOLECUMETICS, LTD. (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0609310-A1 | N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-10 | — | — | EP | disclosed |
| WO-1994017036-A1 | S-LIPOPHILIC ALIPHATIC CARBONYL [N-MERCAPTOACYL-(AMINO ACID OR PEPTIDE)] COMPOUNDS AS ANTIHYPERTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-04 | — | — | WO | disclosed |
| WO-1994003494-A1 | CONFORMATIONALLY RESTRICTED MIMETICS OF REVERSE TURNS AND PEPTIDES CONTAINING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1994-02-17 | — | — | WO | disclosed |
| WO-1993024518-A1 | DESIGN AND SYNTHESIS OF A CD4 BETA-TURN MIMETIC FOR INHIBITING THE BINDING OF HIV GP120 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1993-12-09 | — | — | WO | disclosed |
| EP-0539848-A1 | N-(mercaptoacyl)amino acids, methods of their preparation and therapeutic use, and pharmaceutical compositions containing them | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993008162-A1 | N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-29 | — | — | WO | disclosed |
| US-5166212-A | Hypotensive agents, analgesics | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| US-5021430-A | Enkephalinase inhibitors, analgesics, hypotensives | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10864217-B2 | Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy | API5, BIRC3, BIRC5 | SLC1A1 4478/4885TACR1 4390/4885ALDH1A1 4300/4885 |
| US-20200317731-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | API5, XIAP, BIRC5 | SLC1A1 4641/4885TACR1 4686/4885ALDH1A1 4556/4885 |
| US-20220119444-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | API5, XIAP, BIRC5 | SLC1A1 4641/4885TACR1 4686/4885ALDH1A1 4556/4885 |
| US-10544188-B2 | Inhibitor of apoptosis protein (IAP) antagonists | API5, XIAP, BIRC5 | SLC1A1 4641/4885TACR1 4686/4885ALDH1A1 4556/4885 |
| US-11111270-B2 | Inhibitor of apoptosis protein (IAP) antagonists | API5, XIAP, BIRC5 | SLC1A1 4641/4885TACR1 4686/4885ALDH1A1 4556/4885 |
| US-11912786-B2 | Inhibitor of apoptosis protein (IAP) antagonists | API5, XIAP, BIRC5 | SLC1A1 4641/4885TACR1 4686/4885ALDH1A1 4556/4885 |
| US-20200121693-A1 | Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy | API5, BIRC3, BIRC5 | SLC1A1 4478/4885TACR1 4390/4885ALDH1A1 4300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.