Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790848 | 0.87 | MAOB (0.58) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL20799424 | 0.86 | TP53 (0.48) | MAOBTAS1R3TAS1R1ALDH1A1RAB9A | |
| SCHEMBL13791154 | 0.85 | MAOB (0.60) | MAOBCA12CA2CA4CA6 | |
| SCHEMBL5947962 | 0.84 | MAOB (0.52) | MAOBMAOAALDH1A1RAB9AKDM4E | |
| SCHEMBL1066982 | 0.76 | TAS1R3 (0.56) | MAOBCA12CA2CA4CA6 | |
| SCHEMBL11559549 | 0.76 | MAOB (0.49) | MAOBCA12CA2CA4CA6 | |
| SCHEMBL24766804 | 0.74 | GAA (0.49) | ALDH1A1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9430490 | 0.74 | MAOB (0.49) | MAOBCA12CA2CA4CA6 | |
| SCHEMBL17996501 | 0.73 | TAS1R3 (0.53) | MAOBCA12CA2CA4CA6 | |
| SCHEMBL9204717 | 0.73 | MAOB (0.46) | MAOBCA12CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |