Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | EPOR | P19235 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425407 | 1.00 | PPARG (0.55) | PPARGPPARALTA4HLAP3ALOX5 | |
| SCHEMBL7296822 | 0.86 | CYP1A2 (0.48) | PTGS1 | |
| SCHEMBL3803671 | 0.83 | PPARG (0.59) | PPARGPPARALTA4HLAP3ALOX5 | |
| SCHEMBL8382278 | 0.82 | BCHE (0.48) | PPARGPPARALTA4HLAP3ALOX5 | |
| SCHEMBL3105737 | 0.79 | LTA4H (0.46) | PPARGPPARALTA4HLAP3ALOX5 | |
| SCHEMBL2443383 | 0.79 | LTA4H (0.55) | PPARGPPARALTA4HLAP3ALOX5 | |
| SCHEMBL5811902 | 0.79 | LTA4H (0.80) | PPARGPPARALTA4HLAP3FFAR1 | |
| SCHEMBL2438787 | 0.78 | LTA4H (0.60) | PPARGPPARALTA4HLAP3ALOX5 | |
| SCHEMBL1069493 | 0.78 | PPARG (0.67) | PPARGPPARALTA4HLAP3PTGS1 | |
| SCHEMBL2164145 | 0.78 | PPARG (0.67) | PPARGPPARALTA4HLAP3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |