Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415948 | 0.81 | F2 (0.38) | F2F10KLK1CTRC | |
| SCHEMBL7422449 | 0.69 | F2 (0.34) | F2 | |
| SCHEMBL7422444 | 0.69 | F2 (0.34) | F2 | |
| SCHEMBL17492502 | 0.69 | PARP1 (0.38) | F2 | |
| SCHEMBL7421168 | 0.69 | CYP3A4 (0.30) | — | |
| SCHEMBL7419402 | 0.68 | F2 (0.41) | F2 | |
| SCHEMBL7419399 | 0.68 | F2 (0.41) | F2 | |
| SCHEMBL8986732 | 0.68 | F2 (0.41) | F2 | |
| SCHEMBL7423714 | 0.67 | SRC (0.47) | F2 | |
| SCHEMBL7417421 | 0.67 | F2 (0.40) | F2F10KLK1CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |