Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 16/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
| ▸ | PROC | P04070 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897345 | 0.86 | PRSS1 (0.49) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL27478261 | 0.84 | F10 (0.48) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL27495114 | 0.80 | PRSS1 (0.51) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL27479044 | 0.78 | L3MBTL1 (0.51) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL6049827 | 0.78 | F10 (0.48) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL7413859 | 0.77 | F10 (0.56) | PLGF10PROCF2 | |
| SCHEMBL24322923 | 0.76 | F10 (0.57) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL24322934 | 0.76 | F10 (0.58) | PLGF10PROCF2 | |
| SCHEMBL8000015 | 0.76 | F10 (0.53) | PRSS1PRSS2PRSS3LOXL2PLG | |
| SCHEMBL24323873 | 0.76 | F10 (0.58) | PLGF10PROCF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |