Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331551 | 0.83 | TDP1 (0.56) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| SCHEMBL33928 | 0.83 | TDP1 (0.56) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| SCHEMBL33927 | 0.83 | TDP1 (0.56) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| SCHEMBL1531678 | 0.83 | TDP1 (0.56) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| SCHEMBL1330911 | 0.83 | TDP1 (0.56) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10424136 | 0.81 | TDP1 (0.54) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10445714 | 0.81 | TDP1 (0.54) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| SCHEMBL7251351 | 0.81 | TDP1 (0.54) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| Methane SCHEMBL6442579 | 0.81 | TDP1 (0.54) | TDP1GAAHSD17B10ALDH1A1TSHR | |
| SCHEMBL13020267 | 0.81 | TDP1 (0.54) | TDP1GAAHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287605-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002363-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1988-04-07 | — | — | WO | disclosed |