SCHEMBL7419747

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nearest known ligand 0.46

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	ENPEP	Q07075	18/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7461891	0.82	ENPEP (0.46)	ENPEP
SCHEMBL30229773	0.80	F2 (0.44)	ENPEP
SCHEMBL4086550	0.80	NPY4R (0.45)	—
SCHEMBL30496682	0.80	ENPEP (0.44)	ENPEP
SCHEMBL4082489	0.80	NPY4R (0.49)	—
SCHEMBL31394924	0.80	ENPEP (0.55)	ENPEP
SCHEMBL31198201	0.79	ENPEP (0.52)	ENPEP
SCHEMBL30974368	0.79	ENPEP (0.48)	ENPEP
SCHEMBL30229891	0.79	NPY4R (0.44)	—
SCHEMBL31232977	0.79	GNPAT (0.51)	ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0431113-A4	ATRIAL PEPTIDE DERIVATIVES	—	1992-01-22	—	—	EP	disclosed
EP-0431113-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1991-06-12	—	—	EP	disclosed
WO-1990014362-A1	ATRIAL PEPTIDE DERIVATIVES	ABBOTT LABORATORIES (US)	1990-11-29	—	—	WO	disclosed