Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 15/20 | 0.52 |
| ▸ | FNTB | P49356 | 15/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 13/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427698 | 0.88 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7422067 | 0.88 | FNTA (0.42) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8425396 | 0.86 | FNTA (0.43) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8040881 | 0.86 | FNTA (0.45) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8424616 | 0.84 | F10 (0.57) | F10 | |
| SCHEMBL7419778 | 0.82 | HDAC1 (0.48) | FNTAFNTBPGGT1BKCNH2HDAC1 | |
| SCHEMBL7427696 | 0.82 | HDAC1 (0.41) | FNTAFNTBPGGT1BKCNH2HDAC1 | |
| SCHEMBL7423307 | 0.82 | F10 (0.39) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7422884 | 0.82 | FNTA (0.50) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL7424679 | 0.81 | FNTA (0.59) | FNTAFNTBPGGT1BKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |