Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 7/20 | 0.36 |
| ▸ | FNTB | P49356 | 7/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | S100A9 | P06702 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325183 | 0.86 | F10 (0.44) | F10F2 | |
| SCHEMBL7419783 | 0.82 | FNTA (0.52) | F10FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8425627 | 0.82 | F10 (0.61) | F10F2 | |
| SCHEMBL27493529 | 0.81 | TRPA1 (0.36) | F10F2FNTAFNTBPGGT1B | |
| SCHEMBL7422788 | 0.81 | TRPA1 (0.36) | F10F2FNTAFNTBPGGT1B | |
| SCHEMBL7416243 | 0.81 | TRPA1 (0.36) | F10F2FNTAFNTBPGGT1B | |
| SCHEMBL8040094 | 0.81 | F2 (0.38) | F10F2FNTAFNTBPGGT1B | |
| SCHEMBL2330001 | 0.81 | F2 (0.38) | F10F2FNTAFNTBPGGT1B | |
| SCHEMBL7422067 | 0.80 | FNTA (0.42) | F10F2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL2326785 | 0.80 | TRPA1 (0.35) | F10F2CYP3A4TRPA1S100A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |