Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 7/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419971 | 1.00 | ESR1 (0.39) | ESR1ESR2F10HDAC6TYRO3 | |
| SCHEMBL7423483 | 0.88 | ESR1 (0.42) | ESR1ESR2F10F2USP30 | |
| SCHEMBL7478447 | 0.85 | F10 (0.42) | F10F2PRSS1 | |
| SCHEMBL7478435 | 0.85 | F10 (0.42) | F10F2PRSS1 | |
| SCHEMBL8567424 | 0.84 | ESR1 (0.40) | ESR1ESR2F10HDAC6TYRO3 | |
| SCHEMBL8567428 | 0.84 | ESR1 (0.40) | ESR1ESR2F10HDAC6TYRO3 | |
| SCHEMBL8568710 | 0.79 | F10 (0.39) | ESR1ESR2F10F2PRSS1 | |
| SCHEMBL8568715 | 0.79 | F10 (0.39) | ESR1ESR2F10F2PRSS1 | |
| SCHEMBL7476598 | 0.79 | USP30 (0.38) | ESR1ESR2F10F2USP30 | |
| SCHEMBL7469775 | 0.75 | F10 (0.37) | ESR1ESR2F10F2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |