Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.37 |
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | KHK | P50053 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476598 | 0.87 | USP30 (0.38) | F10F2USP30PRSS1KHK | |
| SCHEMBL7478435 | 0.79 | F10 (0.42) | F10F2PRSS1 | |
| SCHEMBL7478447 | 0.79 | F10 (0.42) | F10F2PRSS1 | |
| SCHEMBL7470577 | 0.77 | KHK (0.43) | F10F2PRSS1KHKHTR2C | |
| SCHEMBL7470587 | 0.77 | KHK (0.43) | F10F2PRSS1KHKHTR2C | |
| SCHEMBL7423483 | 0.76 | ESR1 (0.42) | F10F2USP30PRSS1ESR1 | |
| SCHEMBL8567424 | 0.75 | ESR1 (0.40) | F10F2USP30PRSS1KHK | |
| SCHEMBL8567428 | 0.75 | ESR1 (0.40) | F10F2USP30PRSS1KHK | |
| SCHEMBL7419973 | 0.75 | ESR1 (0.39) | F10F2USP30PRSS1ESR1 | |
| SCHEMBL7419971 | 0.75 | ESR1 (0.39) | F10F2USP30PRSS1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |