Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139244 | 0.94 | TSHR (0.67) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL7260670 | 0.93 | TSHR (0.67) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL10352436 | 0.93 | TSHR (0.67) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL10352591 | 0.93 | TSHR (0.67) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL10353332 | 0.93 | TSHR (0.67) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL4379441 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL30584931 | 0.90 | ALDH1A1 (0.63) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL13621146 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL14413192 | 0.86 | ALDH1A1 (0.69) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL13006879 | 0.85 | ALDH1A1 (0.70) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |
| EP-0223647-B1 | ALKYL CARBOXAMIDES OF PYRIDYL ALKYL AMINES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | S.A. PANMEDICA Société dite: (FR) | 1990-08-01 | — | — | EP | claimed |