Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475673 | 0.91 | KDM4E (0.59) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL1153713 | 0.91 | KDM4E (0.59) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL1153711 | 0.91 | KDM4E (0.59) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL6579390 | 0.80 | HTR2A (0.53) | KDM4ELMNAMAPK1 | |
| SCHEMBL6579394 | 0.80 | HTR2A (0.53) | KDM4ELMNAMAPK1 | |
| SCHEMBL7875715 | 0.78 | KDM4E (0.77) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL7875720 | 0.78 | KDM4E (0.77) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL7566427 | 0.76 | TAAR1 (0.57) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL27549428 | 0.76 | EPHX1 (0.74) | SLC7A5TAAR1SLC6A2EPHX1ANPEP | |
| Hydrochloric Acid SCHEMBL29101369 | 0.75 | KDM4E (0.58) | KDM4ELMNAMAPK1SLC7A5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |