Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875715 | 1.00 | KDM4E (0.77) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL1131200 | 0.89 | KDM4E (0.96) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL1262139 | 0.89 | KDM4E (0.96) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL294458 | 0.89 | KDM4E (0.96) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| Acetic Acid SCHEMBL8841092 | 0.81 | KDM4E (0.81) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| Acetic Acid SCHEMBL8841087 | 0.81 | KDM4E (0.81) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL7420164 | 0.78 | KDM4E (0.51) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL1153586 | 0.78 | KDM4E (0.75) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL1153584 | 0.78 | KDM4E (0.75) | KDM4ELMNAMAPK1SLC7A5TAAR1 | |
| SCHEMBL7566427 | 0.77 | TAAR1 (0.57) | KDM4ELMNAMAPK1SLC7A5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941212-B1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | DEGUSSA (DE) | 2001-03-21 | — | — | EP | disclosed |
| US-6180837-B1 | Process for the catalytic enantioselective reduction of ketones | DEGUSSA-HUELS AG (DE) | 2001-01-30 | — | — | US | disclosed |
| EP-0941212-A1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | Degussa-Hüls Aktiengesellschaft (DE) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022415-A1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | Degussa-Hüls Aktiengesellschaft (DE) | 1998-05-28 | — | — | WO | disclosed |