Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 18/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420161 | 1.00 | OPRD1 (0.56) | OPRD1OPRK1TAS2R14GAATSHR | |
| SCHEMBL475639 | 0.91 | TSHR (0.50) | OPRD1OPRK1GAATSHRNPBWR1 | |
| SCHEMBL1639928 | 0.91 | TSHR (0.50) | OPRD1OPRK1GAATSHRNPBWR1 | |
| SCHEMBL1834351 | 0.91 | TSHR (0.50) | OPRD1OPRK1GAATSHRNPBWR1 | |
| Bromide SCHEMBL7457265 | 0.90 | TSHR (0.49) | OPRD1OPRK1TAS2R14GAATSHR | |
| SCHEMBL5319502 | 0.83 | NR4A1 (0.53) | — | |
| SCHEMBL5319504 | 0.83 | NR4A1 (0.53) | — | |
| SCHEMBL13110184 | 0.83 | NR4A1 (0.53) | — | |
| SCHEMBL1236268 | 0.82 | TSHR (0.55) | OPRK1GAATSHRNPBWR1KMT2A | |
| SCHEMBL6478257 | 0.81 | POLB (0.50) | OPRD1OPRK1GAATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |