Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.46 |
| ▸ | CTRC | Q99895 | 5/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7522836 | 0.99 | F2 (0.52) | F2PRSS2CTRCF10 | |
| Hydrochloric Acid SCHEMBL5866303 | 0.92 | F2 (0.50) | F2PRSS2CTRCF10 | |
| Hydrochloric Acid SCHEMBL5866300 | 0.92 | F2 (0.50) | F2PRSS2CTRCF10 | |
| SCHEMBL7429007 | 0.80 | F2 (0.52) | F2PRSS2CTRC | |
| SCHEMBL7522874 | 0.79 | F2 (0.75) | F2PRSS2CTRCF10 | |
| Hydrochloric Acid SCHEMBL5866301 | 0.79 | F2 (0.52) | F2PRSS2CTRC | |
| SCHEMBL7428089 | 0.78 | PGR (0.40) | F2 | |
| SCHEMBL7428082 | 0.78 | PGR (0.40) | F2 | |
| Hydrochloric Acid SCHEMBL5866088 | 0.78 | PGR (0.39) | F2 | |
| Hydrochloric Acid SCHEMBL5866086 | 0.78 | PGR (0.39) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917528-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | Astra Aktiebolag (SE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998001422-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRA AKTIEBOLAG (SE) | 1998-01-15 | — | — | WO | disclosed |