Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415866 | 1.00 | BCHE (0.39) | BCHEGAAMAPTPKMALDH1A1 | |
| SCHEMBL7419000 | 1.00 | BCHE (0.39) | BCHEGAAMAPTPKMALDH1A1 | |
| SCHEMBL5962212 | 0.78 | SMN1; SMN2 (0.45) | PKMALDH1A1SMN1; SMN2CTSCMEN1 | |
| SCHEMBL6367353 | 0.76 | CYP2D6 (0.50) | PKMALDH1A1SMN1; SMN2CTSCTP53 | |
| SCHEMBL3299433 | 0.76 | MAOB (0.40) | SMN1; SMN2SIGMAR1CTSCTDP1 | |
| SCHEMBL4439566 | 0.74 | POLB (0.44) | CTSCMEN1KMT2APOLBCTSS | |
| SCHEMBL8688302 | 0.73 | GAA (0.46) | GAAMAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL8690046 | 0.73 | GAA (0.46) | GAAMAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL8688252 | 0.73 | GAA (0.46) | GAAMAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL22587234 | 0.69 | TSHR (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |