Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962212 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDTSHRMMP8ALDH1A1 | |
| SCHEMBL11303515 | 0.83 | TDP1 (0.45) | CYP2D6SMN1; SMN2TSHRTP53MMP8 | |
| SCHEMBL2454845 | 0.82 | TDP1 (0.44) | CYP2D6SMN1; SMN2TSHRTP53KMT2A | |
| SCHEMBL8662418 | 0.81 | TRPA1 (0.45) | TSHRTP53KMT2ARAB9ASLC6A2 | |
| SCHEMBL7693931 | 0.77 | MMP12 (0.49) | SMN1; SMN2HPGDTSHRMMP8ALDH1A1 | |
| SCHEMBL4051389 | 0.77 | CTSC (0.46) | TSHRKMT2ACTSC | |
| SCHEMBL7693929 | 0.77 | MMP12 (0.49) | SMN1; SMN2HPGDTSHRMMP8ALDH1A1 | |
| SCHEMBL5526694 | 0.77 | CTSC (0.46) | TSHRKMT2ACTSC | |
| SCHEMBL7415866 | 0.76 | BCHE (0.39) | SMN1; SMN2TP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL7420267 | 0.76 | BCHE (0.39) | SMN1; SMN2TP53ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063232-B1 | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | DAISO CO LTD (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1464638-A1 | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | DAISO CO., LTD. (JP) | 2004-10-06 | — | — | EP | disclosed |
| EP-1063232-A2 | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | DAISO CO., LTD. (JP) | 2000-12-27 | — | — | EP | disclosed |