Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623506 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5799404 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL27878732 | 0.78 | KMT2A (0.46) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL27642134 | 0.76 | CHRNA7 (0.58) | MEN1KMT2ATDP1CHRNA7 | |
| SCHEMBL9175884 | 0.75 | CYP1A2 (0.42) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL4727617 | 0.75 | CYP1A2 (0.48) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL10831151 | 0.74 | PRMT5 (0.45) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5003351 | 0.71 | BCHE (0.40) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5007086 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL5007090 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004046-A1 | COMPOUNDS AS PDE IV AND TNF INHIBITORS | RHONE-POULENC RORER LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |