Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.32 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861557 | 0.83 | SCN4A (0.43) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL14743892 | 0.82 | SCN4A (0.40) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL14743621 | 0.82 | SCN4A (0.40) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL7269372 | 0.81 | — | — | |
| SCHEMBL6535567 | 0.77 | SCN4A (0.45) | SCN4ASCN9ASCN3ASCN5ADPP4 | |
| SCHEMBL24074316 | 0.77 | SCN4A (0.35) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL7746797 | 0.76 | SCN4A (0.36) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL11130623 | 0.75 | SCN4A (0.35) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL248746 | 0.75 | NOS2 (0.39) | SCN4ASCN9ASCN3ASCN5AGLI1 | |
| SCHEMBL10326195 | 0.75 | SCN4A (0.46) | SCN4AGLI1DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |