Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673322 | 0.90 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL6239656 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL2126335 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL170164 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL16431209 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL16431372 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL16432811 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL16433240 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL29368070 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL16431614 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840825-B | Hepta-fluoroiso-propyl quinolines and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-11-05 | — | — | CN | disclosed |
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |