Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342245 | 0.72 | CDC25B (0.39) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| Propane SCHEMBL9015822 | 0.66 | MEN1 (0.47) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL9302191 | 0.63 | CYP1A2 (0.41) | ALDH1A1MAPK1L3MBTL1TSHRIDO1 | |
| SCHEMBL16504821 | 0.63 | MEN1 (0.33) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| Ethylbenzene SCHEMBL3663827 | 0.61 | TP53 (0.82) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| Ethane SCHEMBL1628718 | 0.58 | MEN1 (0.53) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| Ethane SCHEMBL27463775 | 0.58 | MEN1 (0.53) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| Ethane SCHEMBL5905674 | 0.58 | MEN1 (0.53) | TP53ALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL198461 | 0.57 | CSNK2A2 (0.52) | TP53ALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL3920125 | 0.57 | TP53 (0.43) | TP53ALDH1A1MAPK1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001004107-A1 | SUBSTITUTED α,β-ANELLATED BUTYROLACTONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-18 | — | — | WO | claimed |