Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700506 | 0.75 | KMT2A (0.39) | CDC25BMEN1KMT2ALMNAMAPT | |
| SCHEMBL9065440 | 0.75 | MEN1 (0.39) | CDC25BMEN1KMT2ALMNAMAPT | |
| SCHEMBL7420856 | 0.72 | TP53 (0.38) | LMNAMAPTALDH1A1MAPK1RAB9A | |
| SCHEMBL4394784 | 0.72 | TAAR1 (0.38) | MEN1KMT2ALMNAMAPTRAB9A | |
| SCHEMBL6540450 | 0.72 | MAOA (0.38) | CDC25BMEN1KMT2ALMNAMAPT | |
| SCHEMBL1412991 | 0.71 | S100A4 (0.39) | CDC25BMEN1KMT2ALMNAMAPT | |
| SCHEMBL5423240 | 0.70 | CDC25B (0.45) | CDC25BMEN1KMT2ALMNAMAPT | |
| SCHEMBL16286604 | 0.70 | GSK3B (0.46) | CDC25BMEN1KMT2ALMNAMAPT | |
| Ether SCHEMBL9341472 | 0.67 | CDC25B (0.37) | CDC25BMEN1KMT2ALMNAMAPT | |
| SCHEMBL7993982 | 0.65 | CDC25B (0.45) | CDC25BMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259462-A1 | 1,4-DIHYDROPYRIDINES | Whitby Research Incorporated (US) | 1988-03-16 | — | — | EP | claimed |
| WO-1987005512-A1 | 1,4-DIHYDROPYRIDINES | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1987-09-24 | — | — | WO | claimed |