Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409742 | 0.80 | CASP1 (0.74) | CASP1 | |
| SCHEMBL7414944 | 0.79 | CASP1 (1.00) | CASP1 | |
| SCHEMBL7437239 | 0.78 | CASP1 (0.71) | CASP1 | |
| SCHEMBL8055389 | 0.77 | CASP1 (0.67) | CASP1 | |
| SCHEMBL7411874 | 0.77 | CASP1 (0.70) | CASP1 | |
| SCHEMBL7416865 | 0.76 | CASP1 (1.00) | CASP1 | |
| SCHEMBL7416411 | 0.76 | CASP1 (0.66) | CASP1 | |
| SCHEMBL7448796 | 0.75 | CASP1 (1.00) | CASP1 | |
| SCHEMBL7434497 | 0.75 | CASP1 (0.65) | CASP1 | |
| SCHEMBL7449130 | 0.75 | CASP1 (0.69) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001019373-A2 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |
| EP-0998300-A1 | METHODS AND COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-10 | — | — | EP | disclosed |
| US-5919790-A | ANTIINFLAMMATORY AGENT; THERAPY FOR STROKE, SEPTIC SHOCK;ALZHEIMER*S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1998041232-A2 | COMPOSITIONS FOR MODULATING RESPONSIVENESS TO CORTICOSTEROIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-24 | — | — | WO | disclosed |