Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.67 |
| ▸ | F2 | P00734 | 12/20 | 0.67 |
| ▸ | PLG | P00747 | 1/20 | 0.67 |
| ▸ | PLAT | P00750 | 1/20 | 0.67 |
| ▸ | PROC | P04070 | 1/20 | 0.67 |
| ▸ | KLK6 | Q92876 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2324840 | 0.94 | F10 (0.60) | F10F2PLGPLATPROC | |
| SCHEMBL2330458 | 0.79 | F10 (0.74) | F10F2PLGPLATPROC | |
| SCHEMBL7550978 | 0.77 | F10 (0.68) | F10F2PLGPLATPROC | |
| SCHEMBL2332489 | 0.77 | F10 (0.97) | F10F2PLGPLATPROC | |
| SCHEMBL2330097 | 0.77 | KLK6 (0.76) | F10F2PLGPLATPROC | |
| SCHEMBL8425320 | 0.77 | KLK6 (0.78) | F10F2PLGPLATPROC | |
| SCHEMBL7213544 | 0.77 | F10 (0.67) | F10F2PLGPLATPROC | |
| Hydrochloric Acid SCHEMBL7423366 | 0.76 | KLK6 (0.76) | F10F2PLGPLATPROC | |
| SCHEMBL2333265 | 0.76 | F10 (0.77) | F10F2PLGPLATPROC | |
| SCHEMBL8423783 | 0.76 | F10 (0.72) | F10F2PLGPLATPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-A4 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0853618-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |