Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427113 | 0.84 | ITGA4 (0.47) | ITGA4ITGB1 | |
| SCHEMBL7427128 | 0.84 | ITGA4 (0.47) | ITGA4ITGB1 | |
| SCHEMBL7425032 | 0.84 | ITGA4 (0.64) | ITGA4ITGB1LMNAL3MBTL1 | |
| SCHEMBL7389620 | 0.84 | ITGA4 (0.53) | ITGA4ITGB1 | |
| SCHEMBL7535332 | 0.83 | ITGA4 (0.57) | TGFBR1KDM4EITGA4ITGB1LMNA | |
| SCHEMBL7394951 | 0.83 | ITGA4 (0.54) | ITGA4ITGB1BRD4L3MBTL1 | |
| SCHEMBL7430173 | 0.83 | ITGA4 (0.54) | ITGA4ITGB1 | |
| SCHEMBL7429572 | 0.82 | ITGA4 (0.61) | ITGA4ITGB1 | |
| SCHEMBL7426837 | 0.81 | ITGA4 (0.60) | KDM4EITGA4ITGB1L3MBTL1 | |
| SCHEMBL14558521 | 0.79 | ITGA4 (0.57) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |