Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 17/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6732556 | 0.90 | GRM2 (0.73) | GRM2 | |
| SCHEMBL6733862 | 0.88 | GRM2 (0.75) | GRM2CYP3A4 | |
| SCHEMBL6738265 | 0.86 | GRM2 (1.00) | GRM2CYP3A4GAA | |
| SCHEMBL6732452 | 0.85 | GRM2 (0.58) | GRM2CYP3A4 | |
| SCHEMBL6732349 | 0.83 | GRM2 (1.00) | GRM2 | |
| SCHEMBL10560111 | 0.82 | GRM2 (0.74) | GRM2CYP3A4 | |
| SCHEMBL6739402 | 0.82 | GRM2 (0.74) | GRM2CYP3A4 | |
| SCHEMBL6738229 | 0.82 | GRM2 (0.74) | GRM2CYP3A4GAA | |
| SCHEMBL6727524 | 0.82 | GRM2 (1.00) | GRM2CYP3A4GAA | |
| SCHEMBL7417024 | 0.82 | GRM2 (1.00) | GRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |