Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466611 | 0.85 | TSHR (0.43) | TSHRBIRC2HSD17B10MGAMGAA | |
| SCHEMBL4633086 | 0.82 | MME (0.51) | MMESLC1A3SLC1A2MMP2MMP9 | |
| SCHEMBL7453163 | 0.82 | MME (0.54) | MMETSHRSLC1A3SLC1A2KISS1R | |
| SCHEMBL4633090 | 0.82 | MME (0.51) | MMESLC1A3SLC1A2MMP2MMP9 | |
| SCHEMBL4743296 | 0.82 | MME (0.51) | MMESLC1A3SLC1A2MMP2MMP9 | |
| SCHEMBL22432286 | 0.80 | MMP1 (0.40) | MMETSHRSLC1A3SLC1A2KISS1R | |
| SCHEMBL7099851 | 0.80 | MMP1 (0.40) | MMETSHRSLC1A3SLC1A2KISS1R | |
| SCHEMBL8228378 | 0.79 | CA1 (0.39) | TSHRBIRC2HSD17B10MGAMGAA | |
| SCHEMBL11207414 | 0.76 | SLC1A3 (0.40) | MMETSHRSLC1A3SLC1A2KISS1R | |
| SCHEMBL818884 | 0.75 | SLC1A3 (0.36) | MMESLC1A3SLC1A2KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579650-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017460-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1992-10-15 | — | — | WO | disclosed |