Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 12/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.47 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421102 | 0.94 | ITGA4 (0.49) | ITGA4ITGB1CTSAITGB7 | |
| SCHEMBL7427485 | 0.94 | ITGA4 (0.48) | ITGA4ITGB1CTSASMN1; SMN2ITGB7 | |
| SCHEMBL7647725 | 0.90 | ITGA4 (0.51) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7650597 | 0.88 | ITGA4 (0.53) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7387634 | 0.88 | ITGA4 (0.51) | ITGA4ITGB1ITGB7P2RX7 | |
| SCHEMBL7390235 | 0.88 | ITGA4 (0.53) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7383435 | 0.88 | ITGA4 (0.46) | ITGA4ITGB1SMN1; SMN2ITGB7LMNA | |
| SCHEMBL7587960 | 0.88 | ITGA4 (0.47) | ITGA4ITGB1SMN1; SMN2P2RX7 | |
| SCHEMBL7423227 | 0.88 | ITGA4 (0.53) | ITGA4ITGB1CTSASMN1; SMN2ITGB7 | |
| SCHEMBL7419555 | 0.87 | ITGA4 (0.46) | ITGA4ITGB1CTSAITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |