Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.40 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421592 | 0.89 | ITGB3 (0.46) | ITGB3ITGA2BF9F10 | |
| SCHEMBL7419407 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BF10 | |
| SCHEMBL7412389 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BF10 | |
| SCHEMBL8117179 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BF9 | |
| SCHEMBL8117174 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BF9 | |
| SCHEMBL27352804 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BF9 | |
| SCHEMBL7422771 | 0.85 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7423350 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BF9F10 | |
| SCHEMBL8117257 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BF9F10 | |
| SCHEMBL7414401 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BF9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054842-C | Platelet aggregation inhibitors | SEARLE & CO (US) | 2000-07-26 | — | — | CN | claimed |
| CN-1124957-A | 1-amidinophenyl-pyrrolidones piperidinones azetinones as platelet aggregation inhibitors | SEARLE & CO (US) | 1996-06-19 | — | — | CN | claimed |
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | disclosed |
| CN-1054842-C | Platelet aggregation inhibitors | SEARLE & CO (US) | 2000-07-26 | — | — | CN | disclosed |
| CN-1124957-A | 1-amidinophenyl-pyrrolidones piperidinones azetinones as platelet aggregation inhibitors | SEARLE & CO (US) | 1996-06-19 | — | — | CN | disclosed |
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |