Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863376 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 | |
| SCHEMBL11709614 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 | |
| SCHEMBL2845252 | 0.85 | ESR1 (0.50) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 | |
| SCHEMBL7687298 | 0.85 | SIGMAR1 (0.48) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 | |
| Ammonia Solution, Strong SCHEMBL11816347 | 0.84 | ESR1 (0.49) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 | |
| SCHEMBL7632660 | 0.83 | HIF1A (0.43) | — | |
| SCHEMBL30899680 | 0.83 | HIF1A (0.43) | — | |
| SCHEMBL9800436 | 0.83 | CYP1A2 (0.58) | SIGMAR1CYP1A2CYP2C19CYP2D6NQO2 | |
| SCHEMBL6681464 | 0.83 | SIGMAR1 (0.44) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 | |
| SCHEMBL17288559 | 0.83 | SIGMAR1 (0.44) | SIGMAR1CYP1A2CYP2C19CYP2D6SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233945-A1 | HETEROCYCLIC KETONE AND THIOESTER COMPOUNDS AND USES | GPI NIL Holdings, Inc. (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1105112-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2001038304-A1 | HETEROCYCLIC KETONE AND THIOESTER COMPOUNDS AND USES | GPI NIL HOLDINGS, INC. (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-1011650-A1 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | Amgen Inc., (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-2000009108-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-1999014998-A2 | METHOD FOR PREVENTING AND TREATING HEARING LOSS USING SENSORINEUROTROPHIC COMPOUNDS | AMGEN INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| US-4933249-A | Electrostatographic pressure fixing process using encapsulated toner particles | FUJI PHOTO FILM CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4803144-A | Electrophotographic encapsulated pressure fixable toner particles with electroconductive powder coating | FUJI PHOTO FILM CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| US-4699866-A | Preparation of electrostatographic encapsulated toner material improved in powder characteristics | FUJI PHOTO FILM CO., LTD. (JP) | 1987-10-13 | — | — | US | disclosed |
| US-4642281-A | CORE OF POLYMER AND HIGH BOILING SOLVENT; SHELL POLYMER BY IN-SITU POLYMERIZATION | FUJI PHOTO FILM CO., LTD. (JP) | 1987-02-10 | — | — | US | disclosed |
| US-4476211-A | Preparation of electrostatographic toner material provided with surface electroconductivity | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-09 | — | — | US | disclosed |
| US-4476212-A | Preparation of electrostatographic toner material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-09 | — | — | US | disclosed |
| US-4468446-A | Electrostatographic encapsulated toner material improved in powder characteristics | FUJI PHOTO FILM CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4465756-A | Electrostatographic enscapsulated toner material improved in chargeability | FUJI PHOTO FILM CO., LTD. (JP) | 1984-08-14 | — | — | US | disclosed |
| US-4465755-A | Pressure fixable electrostatographic toner material comprising encapsulated particles containing curing agent | FUJI PHOTO FILM CO., LTD. | 1984-08-14 | — | — | US | disclosed |
| US-4455362-A | Preparation of encapsulated electrostatographic toner material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-19 | — | — | US | disclosed |
| US-4442194-A | Preparation of encapsulated electrostatographic toner material using gelatin derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4078934-A | Photosensitive, image-forming composition containing a leuco 2,3-disubstituted-1-indanone and a photooxidant | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-03-14 | — | — | US | disclosed |
| US-3992450-A | PHOTOSENSITIVE COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3931251-A | FROM ANTHRAQUINONE, PURIFICATION USING SULFUROUS ACID SALT | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |