Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423687 | 1.00 | PPARG (0.52) | PPARGALDH1A1GAAKEAP1FPR2 | |
| SCHEMBL27697067 | 0.85 | PPARG (0.56) | PPARGALDH1A1GAAKEAP1MME | |
| SCHEMBL7422544 | 0.82 | ALDH1A1 (0.53) | PPARGALDH1A1KEAP1MME | |
| SCHEMBL7420136 | 0.82 | ALDH1A1 (0.53) | PPARGALDH1A1KEAP1MME | |
| SCHEMBL7422437 | 0.81 | PPARG (0.48) | PPARGALDH1A1MME | |
| SCHEMBL7386258 | 0.80 | ALDH1A1 (0.57) | PPARGALDH1A1GAAKEAP1FPR2 | |
| SCHEMBL7424677 | 0.80 | ALDH1A1 (0.57) | PPARGALDH1A1GAAKEAP1FPR2 | |
| SCHEMBL346889 | 0.80 | MME (0.51) | PPARGMME | |
| SCHEMBL7415561 | 0.79 | PPARG (0.58) | PPARGALDH1A1GAA | |
| SCHEMBL2721340 | 0.79 | PPARG (0.58) | PPARGALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012183-A1 | HETEROCYCLE AMIDES AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 2001-02-22 | — | — | WO | disclosed |