Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387830 | 0.99 | HRH3 (0.57) | HRH3TSHRNPSR1NLRP3CACNA1G | |
| Maleic Acid SCHEMBL7427563 | 0.93 | HRH3 (0.49) | HRH3TSHRNPSR1NLRP3CACNA1G | |
| Fumaric Acid SCHEMBL7427567 | 0.93 | HRH3 (0.49) | HRH3TSHRNPSR1NLRP3CACNA1G | |
| SCHEMBL3384502 | 0.90 | HRH3 (0.58) | HRH3TSHRCACNA1GALDH1A1KDM4E | |
| SCHEMBL7427115 | 0.86 | HRH3 (0.57) | HRH3NPSR1CACNA1GELANEALDH1A1 | |
| SCHEMBL7421852 | 0.85 | HRH3 (0.59) | HRH3NPSR1CACNA1GELANEALDH1A1 | |
| SCHEMBL7424821 | 0.80 | HRH3 (0.59) | HRH3CACNA1GELANEKCNH2RAB9A | |
| Maleic Acid SCHEMBL7424004 | 0.80 | CACNA1G (0.52) | HRH3NPSR1CACNA1GELANEALDH1A1 | |
| Fumaric Acid SCHEMBL7424008 | 0.80 | CACNA1G (0.52) | HRH3NPSR1CACNA1GELANEALDH1A1 | |
| SCHEMBL9714181 | 0.79 | CYP1A2 (0.51) | TSHRNLRP3ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000053589-A1 | PROCESS FOR PREPARING OXAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-09-14 | — | — | WO | disclosed |
| EP-1003748-A2 | PYRROLOPYRROLONE DERIVATIVES AS INHIBITORS OF NEUTROPHIL ELASTASE | GLAXO GROUP LIMITED (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999012933-A2 | PYRROLOPYRROLONE DERIVATIVES AS INHIBITORS OF NEUTROPHIL ELASTASE | GLAXO GROUP LIMITED (GB) | 1999-03-18 | — | — | WO | disclosed |